The Modular Optical Imaging System (OiS200) can perform Widefield Intrinsic Optical Imaging, Fluorescence Imaging and Speckle Imaging. Intrinsic Optical Imaging and fluorescence are a easy and minimally-invasive method for observing brain activity in vivo on both awake and anesthetized mice. Speckle Imaging quantifies cerebral blood flow on surface vessels.

The imaging platform is portable and easy to set up. It offers great configuration flexibility from different camera options to illumination solutions. All images are acquired via a user-friendly software.

The system allows imaging up to ±30º angle. The height can also be adjusted. Illumination arms can be installed in multiple configurations. The plate is made of high quality steel allowing the user to use magnetic accessories. 

Contact us regarding our new microendoscope with cellular resolution of deep brain neural activity designed for awake and freely behaving animals.

All publications with our imaging system can be viewed here.


If you find data analysis to be a daunting task, let our experts simplify the process for you. Check out our new optical imaging data analysis service here.

New product!  Perform imaging on awake mice with our rodent-driven treadmill with head fixation available on our online store.


Integrated & Ergonomic

Save lab space and installation time. Compatible with multiple applications

Modular System

Select LEDs and laser wavelengths, output stimulation type and the quantity of auxiliary inputs/outputs

Better Results

High timing precision for synchronization between stimulation, physiology monitoring and image acquisition​


This imaging system can be customized at a reasonable cost. Contact us for customization options.


  • Cerebral blood flow, neurovascular coupling & functional connectivity studies
  • Neurological disorders
  • Pharmacology
  • Optogenetics
  • Voltage sensitive dies (VSD)
  • Epilepsy
  • Alzheimer’s disease
  • Aging
  • Hypertension
  • Ischemia
  • Strokes
  • Awake head-fixed mice

Widefield Imaging Options

  • Intrinsic Signal Optical Imaging (IOI with red, amber and green LEDs)
  • Fluorescence Imaging (475 nm LED and others available)
  • Laser Speckle Contrast Imaging (LSCI)
imaging options

Vertical Positioning


Multiple cameras

Accessories for the OiS200 can be purchased from our online store

Accessories for the OiS200 can be purchased from our online store

1.5′ (width) X 2′ (depth) X 2′ (height)
Frame Rate
50 fps at 1024 X 1024, up to 1000 fps
Exposure Time
>0.1 ms
Output Stimulation
Digital (8 bits) and Analog (2 channels)
8 inputs, 10 kSamples/second

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